李浩森

副教授 / 硕士生导师

所属平台：演化与基因组

研究领域：昆虫生态与进化，害虫生物防治

联系邮箱： lihaosen3@mail.sysu.edu.cn

联系地址： 深圳市光明区公常路66号中山大学医学园二栋1408

基本信息

姓名：李浩森

性别：男

职称：副教授

导师类型：硕士生导师

ResearchGate网址：https://www.researchgate.net/profile/Hao-Sen-Li

本团队开发的瓢虫生物数据库网址：http://www.ladybirdbase.com

研究内容

本团队围绕天敌昆虫与生物防治，构建了DIET–DNA–DATA的“3D”研究体系：

DIET 聚焦瓢虫等天敌昆虫的食物范围与取食偏好，通过生命史测定、行为学实验和人工饲料研发，探索提升生物防治效率的生态学基础；

DNA 从分子水平解析天敌昆虫食性与取食行为的决定机制，并结合宏条形码等分子技术，揭示天敌昆虫在自然条件下的真实食谱；

DATA 整合生物学、生态学与组学数据，构建天敌昆虫的生物数据库，并融合AI与知识库方法，开发面向生物防治研究与应用的决策支持工具。

学生可在统一的研究框架中系统学习昆虫生态学、分子生物学与数据科学，培养跨尺度、跨技术的综合研究能力，为传统害虫生物防治领域注入新鲜的力量。

课题组拟于2026年招收2名专业型硕士研究生，欢迎加入！

主讲课程

本科课程：《动物学实验》的无脊椎动物实验部分，《生物学野外实习》的昆虫学实习部分，《实验安全》的生物实验安全部分

公选课程：《动物进化之旅》

研究生课程：《昆虫系统学》

工作经历

2022年8月至今，中山大学，生态学院，副教授

2017年1月-2022年7月，中山大学，生命科学学院，特聘副研究员

教育背景

2014年6月-2016年12月，中山大学，生命科学学院，动物学，理学博士

2011年9月-2014年6月，南京农业大学，植物保护学院，农业昆虫与害虫防治，农学硕士

2007年9月-2011年6月，南京农业大学，植物保护学院，植物保护，农学学士

主要奖励

江苏省优秀硕士学位论文、研究生国家奖学金

主持项目

  1. 深圳市科技计划项目，瓢虫生物大数据平台构建及AI驱动的资源挖掘与应用，2026年1月1日-2028年12月31日
  2. 广东省动物保护与资源利用重点实验室开放基金课题，天敌瓢虫对草地贪夜蛾高效控害的品系选育，2023年9月-2025年8月
  3. 国家自然科学基金面上项目，瓢虫对猎物共生菌的免疫防御研究，2022年1月-2025年12月
  4. 广州市基础与应用基础研究项目，利用营养基因组学优化捕食性天敌孟氏隐唇瓢虫的饲养系统，2021年4月-2023年4月
  5. 广东省基础与应用基础研究基金自然科学基金面上项目，瓢虫基因组进化与食性关联研究，2021年1月-2023年12月
  6. 国家自然科学基金青年基金项目，瓢虫对食物改变的适应和食性进化研究，2018年1月-2020年12月
  7. 中山大学高校基本科研业务费青年教师培育项目，外来天敌孟氏隐唇瓢虫种群混合和入侵演变潜力研究，2018年1月-2020年12月

论文论著

  1. Yi-Fei Sun, Kun-Yu Yang, Hao Li, Yuan-Sen Liang, Li-Qun Cai, Jia-Yi Xie, You-Wen Zhang, Jia-Yong Liang, Qian Mou, Ying-Min Wang, Dan Chen, Meng-Xue Qi, Luis Carlos Ramos Aguila, Muhammad Asghar Hassan, Hao-Sen Li*, Hong Pang*. LadybirdBase: A comprehensive biology, ecology, and omics resource for ladybird beetles (Coccinellidae). Insect Science, 2026, https://doi.org/10.1111/1744-7917.70231.
  2. Yuan-Sen Liang, Yi-Fei Sun, Ying-Min Wang, Kun-Yu Yang, Hao Li, Luis Carlos Ramos Aguila, Hao-Sen Li*, Hong Pang*. Identication and functional characterization of a beta-glucosidase gene involved in solanine degradation in the ladybird beetle Henosepilachna vigintioctopunctata. Pest Management Science, 2026, https://doi.org/10.1002/ps.70499.
  3. Kun-Yu Yang, Yi-Fei Sun, Yuan-Sen Liang, Hao Li, Meng-Xue Qi, Zhaowei Wang, Luis Carlos Ramos Aguila, Li-Qun Cai, Hao-Sen Li*, Hong Pang*. Horizontally transferred NADAR genes contribute to immune defense of ladybird beetles against bacterial infection. Insect Biochemistry and Molecular Biology, 2025, 184, 104397.
  4. Hong Pang*, Hao-Sen Li*. New Advances in the Genetics and Evolution of Ladybird Beetles for Biological Control. Insects, 2025, 16, 753.
  5. Hao Li, Li-Qun Cai, Qian Mou, You-Wen Zhang, Hao-Sen Li*, Hong Pang. Research progress on the diversity and host interaction of an aphid symbiont, Serratia symbiotica. Journal of Environmental Entomology, 2025, 47, 1065-1071.
  6. Yu‑Hao Huang, Hermes E. Escalona, Yi‑Fei Sun, Pei‑Fang Zhang, Xue‑Yong Du, Sen‑Rui Gong, Xue‑Fei Tang, Yuan‑Sen Liang, Dan Yang, Pei‑Tao Chen, Huan‑Ying Yang, Mei‑Lan Chen, Bruno Hüttel, Ondrej Hlinka, Xingmin Wang, Karen Meusemann, Adam Ślipiński, Andreas Zwick, Robert M. Waterhouse, Bernhard Misof, Oliver Niehuis, Hao‑Sen Li*, Hong Pang*. Molecular evolution of dietary shifts in ladybird beetles (Coleoptera: Coccinellidae): from fungivory to carnivory and herbivory. BMC Biology, 2025, 23, 67.
  7. Mei-Lan Chen, Yu-Hao Huang*, Li-Qun Cai, Xiang-Miao Qin, Xin-Yi Meng, Hao-Sen Li*, Hong Pang. Influence of host species, location, and aphid prey on microbial diversity and community dynamics of aphidophagous ladybird beetles in Guangxi, China. Ecology and Evolution, 2025, 15, e71036.
  8. Guannan Li, Yu-Hao Huang, Li-Qun Cai, Qian Mou, Yuan-Sen Liang, Yi-Fei Sun, Hao Li, Kun-Yu Yang, Hao-Sen Li*, Hong Pang*. Gut bacteria facilitate pollinivory of the ladybird beetle Micraspis discolor. Frontiers in Microbiology, 2024, 15, 1475985.
  9. Guannan Li, Pei-Tao Chen, Mei-Lan Chen, Tuo-Yan Chen, Yu-Hao Huang, Xin Lü, Hao-Sen Li*, Hong Pang*. 2024; Effect of Ephestia kuehniella eggs on development and transcriptome of the ladybird beetle Propylea japonica. Insects, 2024, 15, 6.
  10. Xue-Yong Du, Pei-Fang Zhang, Sen-Rui Gong, Yuan-Sen Liang, Yu-Hao Huang, Hao-Sen Li*, Hong Pang*. Discovery of a novel circulation route of free-living Serratia symbiotica mediated by predatory ladybird beetles. FEMS Microbiology Ecology, 2023, 99, 1-8.
  11. Xue-Yong Du, Huan-Ying Yang, Sen-Rui Gong, Pei-Fang Zhang, Pei-Tao Chen, Yuan-Sen Liang, Yu-Hao Huang, Xue-Fei Tang, Qiao-Kui Chen, Patrick De Clercq, Hao-Sen Li*, Hong Pang. Aphidophagous ladybird beetles adapt to an aphid symbiont. Functional Ecology, 2022, 36, 2593-2604.
  12. Yu-Hao Huang, Xue-Yong Du, Pei-Tao Chen, Xue-Fei Tang, Sen-Rui Gong, Pei-Fang Zhang, Huan-Ying Yang, Patrick De Clercq, Hao-Sen Li*, Hong Pang. Is pollinivory in the omnivorous ladybird beetle Micraspis discolor (Coleoptera: Coccinellidae) symbiosis-dependent? Biological Control, 2022,169,104867.
  13. Yu-Hao Huang, Sen-Rui Gong, Hao-Sen Li*, Hong Pang. A review of research on horizontal gene transfer in insects. Journal of Environmental Entomology, 2021, 43, 788-810.
  14. Hao-Sen Li, Hong Pang*. Next generation biological control and its research progress in predatory ladybird beetles. Journal of Environmental Entomology, 2021, 43, 584-593.
  15. Hao-Sen Li, Xue-Fei Tang, Yu-Hao Huang, Ze-Yu Xu, Mei-Lan Chen, Xue-Yong Du, Bo-Yuan Qiu, Pei-Tao Chen, Wei Zhang, Adam Ślipiński, Hermes E. Escalona, Robert M. Waterhouse, Andreas Zwick, Hong Pang*. Horizontally acquired antibacterial genes associated with adaptive radiation of ladybird beetles, BMC Biology, 2021, 19, 7.
  16. Hao-Sen Li, Yu-Hao Huang, Mei-Lan Chen, Zhan Ren, Bo-Yuan Qiu, Patrick De Clercq, Gerald Heckel, Hong Pang*. Genomic insight into diet adaptation in the biological control agent Cryptolaemus montrouzieri. BMC Genomics, 2021, 22, 135.
  17. Mei-Lan Chen, Yu-Hao Huang, Bo-Yuan Qiu, Pei-Tao Chen, Xue-Yong Du, Hao-Sen Li*, Hong Pang*. Changes in life history traits and transcriptional regulation of Coccinellini ladybirds in using alternative prey. BMC Genomics, 2020, 21, 44.
  18. Hao-Sen Li, Gerald Heckel, Yu-Hao Huang, Wei-Jian Fan, Adam Ślipiński, Hong Pang*. Genomic changes in the biological control agent Cryptolaemus montrouzieri associated with introduction. Evolutionary Applications, 2019, 12, 989-1000.
  19. Mei-Lan Chen, Tao Wang, Yu-Hao Huang, Bo-Yuan Qiu, Hao-Sen Li*, Hong Pang*. Physiological and evolutionary changes in a biological control agent during prey shifts over several generations. Frontiers in Physiology, 2018, 9, 971.
  20. Hao-Sen Li, Shang-Jun Zou, Patrick De Clercq, Hong Pang*. 2018. Population admixture can enhance establishment success of the introduced biological control agent Cryptolaemus montrouzieri. BMC Evolutionary Biology, 2018, 18, 36.
  21. Hao-Sen Li, Xin-Yu Liang, Shang-Jun Zou, Yang Liu, Patrick De Clercq, Adam Ślipiński, Hong Pang*. New EST-SSR markers reveal strong genetic differentiation in native and introduced populations of the mealybug destroyer Cryptolaemus montrouzieri. Biological Control, 2017, 21-26.
  22. Hao-Sen Li, Chang Pan, Patrick De Clercq, Adam Ślipiński, Hong Pang*. Variation in life history traits and transcriptome associated with adaptation to diet shifts in the ladybird Cryptolaemus montrouzieri. BMC Genomics, 2016, 17, 281.
  23. Hao-Sen Li, Ary A. Hoffmann, Jing-Feng Guo, Yun Zuo, Xiao-Feng Xue, Hong Pang, Xiao-Yue Hong*. Identification of two lineages of host-associated eriophyoid mites predisposed to different levels of host diversification. Molecular Phylogenetics and Evolution, 2016, 105, 235-240.
  24. Hao-Sen Li, Xin-Yu Liang, Shang-Jun Zou, Yang Liu, Patrick De Clercq, Adam Ślipiński, Hong Pang*. Episodic positive selection at mitochondrial genome in an introduced biological control agent. Mitochondrion, 2016, 28, 67-72.
  25. Hao-Sen Li, Hong Pang*. Population genetics of predatory ladybirds and its applications in biological control. Journal of Environmental Entomology, 2015, 38, 221-227.
  26. Hao-Sen Li, Meng-Jie Jin, Adam Ślipiński, Patrick De Clercq, Hong Pang*. Genetic differentiation in native and introduced populations of Cryptolaemus montrouzieri and its implications for biological control programs. Journal of Economic Entomology, 2015, 108, 2458-2464.
  27. Hao-Sen Li, Xiao-Feng Xue, Xiao-Yue Hong*. Homoplastic evolution and host-association of Eriophyoidea (Acari: Prostigmata) conflict with morphological-based taxonomic system. Molecular Phylogenetics and Evolution, 2014, 78, 185-198.
  28. Hao-Sen Li, Xiao-Feng Xue, Xiao-Yue Hong*. Cryptic diversity in host-associated populations of Tetra pinnatifidae (Acari: Eriophyoidea): What do morphometric, mitochondrial and nuclear data reveal and conceal? Bulletin of Entomological Research, 2014, 104, 221-232.
  29. Hao-Sen Li, Yu Liu, Xiao-Feng Xue, Xiao-Yue Hong*. Population structures of Acaphylla theae and Calacarus carinatus from different tea-producing areas of China reveal no host-associated differentiation and recent colonization. Systematic and Applied Acarology, 2014, 19, 113-122.
  30. Hao-Sen Li, Xiao-Feng Xue, Xiao-Yue Hong*. Eriophyoid mites from Qinghai Province, northwestern China with descriptions of nine new species (Acari, Eriophyoidea). ZooKeys, 196, 47-107.