Koyabu Daisuke 小薮大輔

个人经历

2025-今 教授、中山大学

2021-2025    副教授、日本筑波大学

2019-2021    副教授、香港城市大学　

2013-2018    研究助理教授、日本东京大学　     

2011-2013    博士后、瑞士苏黎世大学

教育经历

2008-2011      博士、日本东京大学

2006-2008      硕士、日本京都大学

2003-2004      国費交換留学、加利福尼亚大学伯克利

2001-2006      学士、日本京都大学

学术成就

日本国立研究开发法人科学技术振兴机构“创发性研究支援项目 创发研究人员“采用（2022）。日本政府教育部青年科学家（2016）、日本进化研究学会青年科学家（2014）、德国哺乳动物研究学会青年科学家奖 (Fritz-Frank Award)（2013）、日本哺乳动物研究学会青年科学家奖（2012）。

包括在Nature Communications, PNAS, Current Biology, Philosophical Transactions of the Royal Society B, Proceedings of the Royal Society B等进化学主流期刊发表学术论文70余篇。目前担任Proceedings of the Royal Society B, Mammalian Biology, Journal of Experimental Zoology Part B, PeerJ, Mammal Study, MorphoMuseum等期刊编委或副主编。国際脊椎动物形态学会理事。

论文

75. Kiuno, K., Nishizato, M.; Hu, W.Y., Mitsunaga, S., Shigenaga, C. Shinohara, M., Nochide, K., Murakami, T., Koyabu, D., Takano, A., Koizumi, N., Shimoda, H., Hayasaka, D. Genetic diversity of pathogenic Leptospira spp. harbored by bats in Japan. Microbial Pathogenesis (in press).

74. Meguro, F., Higashiyama, H., Pommery, Y., Wilson, L.A.B., Tu, V.T., Nojiri, T., Fukui, D., Koyabu, D.* The development of orofacial complex in bats: implications for orofacial clefting. J. Anat. 246: 331-344 (2024). 

73. Pommery, Y., Koyabu, D., Meguro, F., Tu, V.T., Ngamprasertwong, T., Wannaprasert, T., Nojiri, T., Wilson, L.A.B. (in press). Prenatal growth patterns of the upper jaw complex with implications for laryngeal echolocation in bats. J. Anat. 246: 345-362 (2024). 

72. Hoshino, Y., Liu, S., Furutera, T., Yamada, T., Koyabu, D., Nukada, Y., Miyazawa, M., Yoda, T., Ichimura, K., Iseki, S., ; Tasaki, J., Takechi, M. Pharmacological inhibition of the spliceosome SF3b complex by Pladienolide-B elicits craniofacial developmental defects in mouse and zebrafish. Birth Defects Researche 116: e2404 (2024).

71. Nojiri, T., Takechi, M., Furutera, T., Brualla, N.L.M., Iseki, M., Fukui, D., Tu, V.T., Meguro, F., Koyabu, D.* Development of the hyolaryngeal architecture in horseshoe bats: Insights into the evolution of the pulse generation for laryngeal echolocation. EvoDevo 15:2 (2024). https://doi.org/10.1186/s13227-024-00221-7

70.  Brualla, N.L.M., Wilson, L.A.B., Tu, V.T., Nojiri, T., Carter, R.T., Ngamprasertwong, T., Wannaprasert, T., Doube, M., Fukui, D., Koyabu, D.* Comparative anatomy of the vocal apparatus in bats and implication for the diversity of laryngeal echolocation. Zoological Journal of the Linnean Society  202: zlad180 (2024). https://doi.org/10.1093/zoolinnean/zlad180

69. Tsutsumi, M., Saito, N., Koyabu, D., Furusawa, C. A deep learning approach for morphological feature extraction based on variational auto-encoder : an application to mandible shape. npj Systems Biology and Applications 9, 30 (2023). https://doi.org/10.1038/s41540-023-00293-6

68. Tu, V.T., Furey, N.M., Görföl, T., Hassanin, A., Arai, S., Koyabu, D., Douangboubpha, B. and Csorba ,G. A taxonomic reassessment of Rhinolophus rex Allen, 1923 and its allies (Chiroptera: Rhinolophidae). Vertebrate Zoology 73: 545-556 (2023). https://doi.org/10.3897/vz.73.e101487

67. Koyabu, D.* Evolution, conservatism, and overlooked homologies of the mammalian skull. Philosophical Transactions of the Royal Society B 378: 20220081 (2023). https://doi.org/10.1098/rstb.2022.0081

66. Chi, T.C., Tu, V.T., Sohn, J.H., Kimura, J., Koyabu, D*. Caudal auricular muscle variations and the evolution of echolocation behavior in pteropodid bats. Journal of Veterinary Medical Science (2023). https://doi.org/10.1292/jvms.23-0128

65. Chi, T.C., Meguro, F., Takechi, M., Furutera, T., Tu, V.T., Higashiyama, H., Sohn, J.H., Nojiri, T., Kimura, J., Koyabu, D*. Anatomy and homology of the caudal auricular muscles in greater short-nosed fruit bat (Cynopterus sphinx). Journal of Veterinary Medical Science (2023).  https://doi.org/10.1292/jvms.23-0088

64. Hoshino, Y., Takechi, M., Moazen, M., Steacy, M., Koyabu, D., Furutera, T., Ninomoiya, Y., Nuri, T., Pauws, E., Iseki, S. Synchondrosis fusion contributes to the progression of postnatal craniofacial dysmorphology in syndromic craniosynostosis. Journal of Anatomy (2023). https://doi.org/10.1111/joa.13790

63. Brualla, N., Wilson, L.A.B., Doube, M., Carter, R.T., McElligott, A.G., Koyabu, D. The vocal apparatus: an understudied tool to reconstruct the evolutionary history of echolocation in bats? Journal of Mammalian Evolution (2023). https://doi.org/10.1007/s10914-022-09647-z

62. Nojiri, T., Werneburg, I, Tu, V.T., Fukui, D., Takechi, M., Iseki, S., Furutera, T., Koyabu, D.* Timing of organogenesis underscores the evolution of neonatal life histories and powered flight in bats. Proceedings of the Royal Society B 290: 20221928 (2023).

61. Higashiyama, H., Koyabu, D., Kurihara, H. Evolution of the therian face through complete loss of the premaxilla. Evolution & Development 25: 103-118 (2023).

60.  Cao, R., Takechi, M., Wang, X., Furutera, T., Nojiri, T., Koyabu, D.*, Li, J.* Temporal and regulatory dynamics of the inner ear transcriptome during development in mice. Scientific Reports 12, 21196 (2022).

59. Amson, E. Scheyer, T., Martinez, Q., Schwermann, A., Koyabu, D., He, K., Ziegler, R. Unique bone microanatomy reveals ancestry of subterranean specializations in mammals. Evolution Letters 6: 552-561 (2022).

58. Cao, R., Li, J., Koyabu, D.* A bibliometric analysis of research trends in bat echolocation studies between 1970 and 2021. Ecological Informatics 69: 101654 (2022).

57. Ito, K., Kodera, R., Koyasu, K., Martinez, Q., Koyabu, D. The development of nasal turbinate morphology of moles and shrews. Vertebrate Zoology 72: 857-881 (2022).

56. Zhang, Z., Yaryhin, O., Koyabu, D., Werneburg, I. Morphological association between muscle attachment and ossification sites in the late cartilaginous skull of tuatara embryos. Journal of Morphology 283 (7): 908-931 (2022).

55.  Abel, P., Pommery, Y. Ford, D.P., Koyabu, D., Werneburg, I. 3D models related to the publication: Skull sutures and cranial mechanics in the Permian reptile Captorhinus aguti and the evolution of the temporal region in early amniotes. Morphomuseum 8 (167): 167.

54. Abel, P., Pommery, Y. Ford, D.P., Koyabu, D., Werneburg, I. Skull sutures and cranial mechanics in the Permian reptile Captorhinus aguti and the evolution of the temporal region in early amniotes. Frontiers in Ecology and Evolution 841784 (2022).

53. Nojiri, T., Tu, V.T., Sohn, J.H., Koyabu, D.* On the sequence heterochrony of cranial ossification of bats in the light of Haeckel’s recapitulation theory. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 338: 137-148 (2022).

52. Nojiri, T., Fukui, D., Werneburg, I., Saitoh, T., Endo, H., Koyabu, D.* Embryonic staging of bats with special reference to Vespertilio sinensis and its cochlear development. Developmental Dynamics 250: 1140-1159 (2021).

51. Nojiri, T., Wilson, L.A.B., López-Aguirre, C., Tu, V.T., Kuratani, S., Ito, K., Higashiyama, H., Son, N.T., Fukui, D., Sadier, A., Sears, K.E., Endo, H., Kamihori, S., Koyabu, D.* Embryonic evidence uncovers convergent origins of laryngeal echolocation in bats. Current Biology 31: 1353-1365.e3 (2021).

50. Sohn, J.H., Fukui, D., Nojiri, T., Minowa, K., Kimura, J., Koyabu, D.* Three-dimensional and histological observations on male genital organs of greater horseshoe bat, Rhinolophus ferrumequinum. Journal of Mammalian Evolution 28(2): 559-571 (2021).

49.  Ito, K., Tu, V. T., Eiting, T. P., Nojiri, T., Koyabu, D.* On the embryonic development of the nasal turbinals and their homology in bats. Frontiers in Cell and Developmental Biology 23: 613545 (2021).

48.  Higashiyama, H., Koyabu, D., Hirasawa, T., Werneburg, I., Kuratani, S., Kurihara, H. Mammalian muzzle as an evolutionary novelty. Proceedings of the National Academy of Sciences of the United States of America 118 (44) e2111876118 (2021).

47.  López-Aguirre, C., Wilson, L.A.B., Koyabu, D., Tu, V.T., Hand, S.J. Variation in cross-sectional shape and biomechanical properties of the bat humerus under Wolff’s law. Anatomical Record 304: 1937-1952 (2021).

46. López-Aguirre, C., Hand, S.J., Koyabu, D., Tu, V.T., Wilson, L.A.B. Prenatal developmental trajectories of fluctuating asymmetry in bat humeri. Frontiers in Cell and Developmental Biology 9: 639522 (2021).

45. Tu, V.T., Görföl, T., Csorba, G., Arai, S., Kikuchi, F., Fukui, D., Koyabu, D., Furey, N.M., Bawm, S., Lin, K.S., Alviola, P., Hang, C.T., Son, N.T., Tuan, T.A., Hassanin, A. Integrative taxonomy and biogeography of Asian yellow house bats (Vespertilionidae: Scotophilus) in the Indomalayan Region. Journal of Zoological Systematics and Evolutionary Research 59(3): 772-795 (2021).

44. López-Aguirre, C., Hand, S.J., Koyabu, D., Tu, V.T., Wilson, L.A.B. Phylogeny and foraging behaviour shape modular morphological variation in bat humeri. Journal of Anatomy 238(6): 1312-1329 (2021).

43. Sohn, J.H. Kimura, J., Koyabu, D.* 3D model related to the publication: three-dimensional and histological observations on male genital organs of greater horseshoe bat, Rhinolophus ferrumequinum. Morphomuseum (2020). https://doi.org/10.18563/journal.m3.113

42. Sano, K., Beyene, Y., Katoh, S., Koyabu, D., Endo, H., Sasaki, T., Asfaw, B., Suwa, G. A 1.4-million-year-old bone handaxe from Konso, Ethiopia, shows advanced tool technology in the early Acheulean. Proceedings of the National Academy of Sciences of the United States of America. 117 (31) 18393-18400 (2020). 

41. López-Aguirre, C.*, Hand, S.J., Koyabu, D., Son, N.T. and Wilson, L.A.B. Postcranial heterochrony, modularity, integration and disparity in the prenatal ossification in bats (Chiroptera). BMC Evolutionary Biology 19:75 (2019).

40. López-Aguirre, C.*, Hand, S.J., Koyabu, D., Son, N.T. and Wilson, L.A.B. Prenatal allometric trajectories and the developmental basis of postcranial phenotypic diversity in bats (Chiroptera). Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 332: 36-49 (2019).

39. Ledevin, R., Koyabu, D.* Patterns and constraints of craniofacial variation in colobine monkeys: disentangling the effects of phylogeny, allometry and diet. Evolutionary Biology 46: 14–34 (2019).

38. Oh, J.W., Minami, M.,Ikeda, S.,Takatsuki, S., Oonishi, N, Higuchi, N., Okada, A., Kimura, J., Koyabu, D*. Non-invasive age estimation by cranial suture closure in Japanese sika deer (Cervus nippon). Mammal Study 44(3):147 - 155 (2019).

37. Ito, T.*, Koyabu, D. Biogeographic variation in skull morphology across the Kra Isthmus in dusky leaf monkeys. Journal of Zoological Systematics and Evolutionary Research 56: 599-610 (2018).

36. Nojiri, T., Werneburg, I., Son, N.T., Tu, V.T., Sasaki, T., Maekawa, Y., Koyabu, D.* Prenatal cranial bone development of Thomas’s horseshoe bat (Rhinolophus thomasi): with special reference to petrosal morphology. Journal of Morphology 279(6): 809-827(2018).

35. Koyabu, D.*, Hosojima, M., Endo, H. Into the dark: patterns of middle ear adaptations in subterranean eulipotyphlan mammals. Royal Society Open Science 4: 170608 (2017).

34. Oh, J.W., Oh, H.S., Kimura, J.*, Koyabu, D.* Intraspecific variation of the interparietal suture closure in Siberian roe deer Capreolus pygargus from Jeju Island. Journal of Veterinary Medical Science 79: 2052–2056 (2017).

33. Endo, H.*, Ito, K., Watabe, H., Son, N.T., Koyabu, D. Macroscopic and CT examinations of the mastication mechanism in the southern tamandua. Mammal Study 42: 89-96 (2017).

32. Koyabu, D.* 3D atlas and comparative osteology of the middle ear ossicles among Eulipotyphla (Mammalia, Placentalia). Morphomuseum 3 (2)-e3 (2017). 

31. Koyabu, D.* Prenatal postcranial development in two species of sympatric Japanese wood mice (Apodemus argenteus and A. speciosus): a comparison of arboreal versus terrestrial congeners. Journal of Veterinary Medical Science 79: 952-956 (2017). 

30. Oh, J.W., Kim, Y.K., Yasuda, M., Koyabu, D.*, Kimura, J. Cranial suture closure pattern in water deer and implications of suture evolution in cervids. Mammalian Biology 86:17-20 (2017). 

29. Werneburg, I.*, Laurin, M., Koyabu, D., Sánchez-Villagra, M.R.* Evolution of organogenesis and the origin of altriciality in mammals. Evolution and Development 18(4):229–244 (2016).

28. Ramírez-Chaves, H.*, Wroe, S., Selwood, L., Hinds, L., Leigh C., Koyabu, D., Kardjilov, N., Weisbecker, V.* Mammalian development does not recapitulate suspected key transformations in the evolution of the mammalian middle ear. Proceedings of the Royal Society B 283: 20152606 (2016).

27. Kim, Y.K., Koyabu, D., Lee, H., Kimura, J*. Cranial morphological homogeneity in two subspecies of water deer in China and Korea. Journal of Veterinary Medical Science 77: 1427–1435 (2015).

26. Omura, A.*, Anzai, W., Koyabu, D., Endo, H. Positional strategy of trunk muscles among aquatic, semi-aquatic, and terrestrial species in Urodela. Journal of Veterinary Medical Science 77: 1043–1048 (2015).

25. Omura, A.*, Anzai, W., Koyabu, D., Endo, H. Ontogenetic changes of tunk muscle structure in the Japanese black salamander (Hynobius nigrescens). Journal of Veterinary Medical Science 77: 931-936 (2015).

24. Mori, K.*, Suzuki S., Koyabu, D., Kimura, J., Han, S.Y., Endo, H. Comparative functional anatomy of hindlimb muscles and bones with reference to aquatic adaptation of the sea otter. Journal of Veterinary Medical Science 77: 571–578 (2015).

23. Koyabu, D.*, Son, N.T. Patterns of postcranial ossification and sequence heterochrony in bats: life histories and developmental trade-offs. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 322: 607–618 (2014). 

22. Endo, H.*, Yamasaki, T., Mori, K., Kudo, K., Koyabu, D. Functional morphology of the enlarged pharynx and hyoid bone of the shoebill. Japanese Journal of Zoo and Wildlife Medicine 19(1)： 21-25 (2014). 

21. Koyabu, D.*, Werneburg, I., Morimoto, N., Zollikofer, C.P.E., Forasiepi, A.M., Endo, H., Kimura, J., Ohdachi, S.D., Son, N.T., Sánchez-Villagra, M.R. Mammalian skull heterochrony reveals modular evolution and a link between cranial development and brain size. Nature Communications 5: 365 (2014).  

20. Omura A.*, Ejima, K., Honda, K., Anzai, W., Taguchi, Y., Koyabu, D., Endo, H. Locomotion pattern and trunk musculoskeletal architecture among Urodela. Acta Zoologica 96: 225–235 (2014).

19. Geiger, M.*, Forasiepi, A.M., Koyabu, D., Sánchez-Villagra, M.R. Heterochrony and postnatal growth in mammals - an examination of growth plates in limbs. Journal of Evolutionary Biology  27: 98–115 (2014).

18. Kim, Y.K.†, Koyabu D.†, Lee, H. Kimura, J.* Sexual Dimorphism of Craniomandibular Size in the Korean Water Deer, Hydropotes inermis argyropus. Journal of Veterinary Medical Science 75(9): 1153–1159 (2013).  †Co-first authors.

17. Meier, P. S., Bickelmann, C., Scheyer, T.M., Koyabu, D., Sánchez-Villagra, M.R.* Evolution of bone compactness in extant and extinct moles (Talpidae): exploring the effects of fossoriality into humeral microstructure of small mammals. BMC Evolutionary Biology 13:55 (2013).

16. Furuuchi, K., Koyabu, D.*, Mori, K., Endo, H. Physiological cross-sectional area of the masticatory muscles in the giraffe (Giraffa camelopardalis). Mammal Study 38: 67-71 (2013).

15. Oshida, T., M., Can, D.N., Son, N.T., Nghia, N.X., Endo, H, Kimura, J., Sasaki, M., Hayashida, A., Takano, A., Koyabu, D., Hayashi, Y.  Phylogenetic position of Callosciurus erythraeus griseimanus from Vietnam in the genus Callosciurus. Mammal Study 38: 41-48 (2013).

14. Endo, H.*, Mori, K., Koyabu, D., Kawada, S. , Komiya, T., Itou, T., Koie, H., Kitagawa, M., and Sakai, T. Functional morphology of the tail in the aardvark. Anatomia, Histologia, Embryologia 42 (2): 90-98 (2013).

13. Koyabu, D.*, Maier, W., Sánchez-Villagra, M.R. Paleontological and developmental evidence resolve the homology and dual embryonic origin of a mammalian skull bone, the interparietal. Proceedings of the National Academy of Sciences of the United States of America 109 (35): 14075-14080 (2012).  

12. Koyabu, D.* and Sánchez, R. New fossil dugong from the Urumaco Formation (Los Dugones de Urumaco, in Spanish). In: Marcelo R Sánchez-Villagra ed., Venezuela Paleontológica. Printworkart Press 301-311 (2012). 

11. Kim, S.-I., Suzuki, S., Oh , J.-W., Koyabu, D., Oshida, T., Lee, H., Min, M.-S., Kimura, J*. Sexual dimorphism of craniodental morphology in the raccoon dog Nyctereutes procyonoides from South Korea. Journal of Veterinary Medical Science  74 (12): 1609-1616 (2012).

10. Koyabu, D.*, Oshida, T., M., Son, N.T., Can, D.N., Nghia, X.N., Dang, X.N., Motokawa, D.N., Kimura, J., Sasaki, M., and Endo, H. Comparison of jaw muscle morphology in two sympatic callosciurine squirrels (Callosciurus erythraeus and Dremomys rufigenis) in Vietnam. Mammal Study 37: 237–242 (2012).

9. Hugi, J.*, Hutchinson, M.N., Koyabu, D., and Sánchez-Villagra, M.R. Heterochronic shifts in the ossification sequences of surface and subsurface-dwelling skinks are correlated with the degree of limb reduction. Zoology 115: 188-198 (2012).

8. Koyabu, D.*, Endo, H., Mitgutsch, C., Suwa, G., Catania, K.C., Zollikofer, C.P.E, Oda, S., Koyasu, K., Ando, A., Sánchez-Villagra, M.R. Heterochrony and developmental modularity of cranial osteogenesis in lipotyphlan mammals. Evo Devo 2: 21 (2011).   " the most accessed paper published in 2011" in Evo Devo.

7. Endo, H.*, Koyabu, D.B., Kimura, J., Rakotondraparany, F., Matsui, A., Yonezawa, T., Shinohara, A. and Hasegawa, M. Quill vibrating mechanism for a sounding apparatus in the streaked tenrec (Hemicentetes semispinosus). Zoological Science 27: 427-432 (2010).

6. Koyabu, D.B.* and Endo, H. Craniodental mechanics and diet in Asian colobines: morphological evidence of mature seed predation and sclerocarpy. American Journal of Physical Anthropology 142:137-148 (2010). 

5. Endo, H.*, Kobayashi, H., Koyabu, D., Hayashida, A., Jogahara, T., Taru, H., Oishi, M., Itou, T., Koie, H. and Sakai, T. The morphological basis of the armor-like folded skin of the greater Indian rhinoceros as a thermoregulator. Mammal Study 34: 209-212 (2009).

4. Endo, H.*, Koyabu, D., Hayashida, A., Oishi, M., Kawada, S. and Komiya, T. The brachial plexus adapted to the semi-elongated neck in the okapi. Mammal Study 34: 195-200 (2009).

3. Koyabu, D.B.*, Oshida, T., Dang, N.X., Can, D.N., Kimura, J., Sasaki, M., Motokawa, M., Son, N.T., Hayashida, A., Shintaku, Y. and Endo, H. Craniodental mechanics and the feeding ecology of two sympatric callosciurine squirrels in Vietnam. Journal of Zoology, London 279 (4): 372-380 (2009). 

2. Koyabu, D.B.* and Endo, H. Craniofacial variation and dietary adaptations in African colobines. Journal of Human Evolution 56: 525-536 (2009). 

1. Koyabu, D.B., Malaivijitnond, S.*, Hamada, Y.  Pelage color variation of Macaca arctoides and its evolutionary implications. International Journal of Primatology 29 (2): 531-541 (2008).